Testosterone cypionate powder:Everything you should know about the amazing steroids!!!
What is Testosterone cypionate?/Testosterone cypionate overview
Testosterone Cypionate is one of the many esterified variants of Testosterone available,usually for bodybuilding and treating ED,others like Testosterone acetate,Testosterone decanoate, Testosterone enanthate,Testosterone phenylpropionate,Testosterone isocaproate,Testosterone propionate,Testosterone Sustanon 250,are all part of the variants of Testosterone.Testosterone Cypionate is most likely the second most popular esterified variant (the first being Testosterone Enanthate). It is an injectable form of Testosterone with a slow rate of release and a longer half-life. However, the release rates and half-life of both Testosterone Cypionate and Testosterone Enanthate are very much identical and the two compounds are easily interchangeable (for example, an individual can easily run a 10 week cycle of Testosterone and switch between Testosterone Enanthate and Testosterone Cypionate seamlessly). Testosterone Cypionate possesses a half-life of approximately 12 days while Testosterone Enanthate possesses a half-life of approximately 10 days – hardly much difference. The interesting fact about Testosterone Cypionate, however, is that it seems to have a distinct favor of popularity among American bodybuilders and athletes over the Enanthate variant. These distinctions are not extreme, however, and the commonality of use and availability of both variants is almost equal with Testosterone Enanthate ever so slightly more popular. Neither variant possesses any advantages over the other.
History of Testosterone Cypionate
Testosterone Cypionate was first created in the mid-1950s, and was released on the prescription drug market under the brand name Depo-Testosterone and manufactured by UpJohn (however, its brand name at first was labeled as Depo-Testosterone cyclopentylpropionate but was shortened for obvious reasons). Unlike Testosterone Enanthate, which is primarily known as an international item, Testosterone Cypionate is known to be the US answer to the Enanthate variant (although Testosterone Enanthate is utilized almost just as equally in the US). Testosterone Cypionate has held such a positive track record that it is in fact still in production by Upjohn (who merged with Pfizer in 2009) today. As Testosterone Cypionate was the American response to the international product Testosterone Enanthate, many American bodybuilders and athletes throughout the 1960s, 70s, and 80s preferred the use of Testosterone Cypionate over the Enanthate variant for no reason other than the support of an American product, very much akin to an issue of pride (once again, the Cypionate and Enanthate variants of Testosterone are both almost 100% identical and there is no practical reason to prefer one compound over the other).Testosterone is the primary androgen found in the body. Endogenous testosterone is synthesized by cells in the testis, ovary, and adrenal cortex. Therapeutically, testosterone is used in the management of hypogonadism, either congenital or acquired. Testosterone is also the most effective exogenous androgen for the palliative treatment of carcinoma of the breast in postmenopausal women. Testosterone was in use in 1938 and approved by the FDA in 1939. Anabolic steroids, derivatives of testosterone, have been used illicitly and are now controlled substances. Testosterone, like many anabolic steroids, was classified as a controlled substance in 1991. Testosterone is administered parenterally in regular and delayed-release (depot) dosage forms. In September 1995, the FDA initially approved testosterone transdermal patches (Androderm); many transdermal forms and brands are now available including implants, gels, and topical solutions. A testosterone buccal system, Striant, was FDA approved in July 2003; the system is a mucoadhesive product that adheres to the buccal mucosa and provides a controlled and sustained release of testosterone. In May 2014, the FDA approved an intranasal gel formulation (Natesto). A transdermal patch (Intrinsa) for hormone replacement in women is under investigation; the daily dosages used in women are much lower than for products used in males. The FDA ruled in late 2004 that it would delay the approval of Intrinsa women's testosterone patch and has required more data regarding safety, especially in relation to cardiovascular and breast health.
What is Testosterone cypionate powder?
Detail of Testosterone cypionate powder as below:
Name: Testosterone Cypionate
CAS: 58-20-8
Molecular Formula: C27H40O3
Molecular Weight: 412.6
Melt Point: 98 - 104ºC
Storage Temp.: 2-8ºC
Color: White or off white Crystal Powder
What form(s) does Testosterone cypionate powder come in?
Testosterone Cypionate is commonly used as an injected oil,also sold in the form of injection.In the market, there are 200mg/ml, 250mg/ml, 300mg/ml, some UGL even made 350mg/ml and 400mg/ml.How does Testosterone cypionate work?
Testosterone cypionate belongs Testosterone,is the class of medications called androgens (male hormones). This medication is used to replace testosterone in men who have conditions caused by low testosterone levels, such as erectile dysfunction (difficulty getting or keeping an erection). There are other possible causes for erectile dysfunction, so testosterone is only used to treat erectile dysfunction that is caused by low testosterone.Testosterone cypionate works by replacing the testosterone that the body is missing. Testosterone cypionate should only be used if testosterone deficiency has been confirmed by symptoms and blood tests.
Mechanism of Action
Endogenous testosterone is responsible for sexual maturation at all stages of development throughout life. Synthetically, it is prepared from cholesterol. The function of androgens in male development begins in the fetus, is crucial during puberty, and continues to play an important role in the adult male. Women also secrete small amounts of testosterone from the ovaries. The secretion of androgens from the adrenal cortex is insufficient to maintain male sexuality.Increased androgen plasma concentrations suppress gonadotropin-releasing hormone (reducing endogenous testosterone), luteinizing hormone, and follicle-stimulating hormone by a negative-feedback mechanism. Testosterone also affects the formation of erythropoietin, the balance of calcium, and blood glucose. Androgens have a high lipid solubility, enabling them to rapidly enter cells of target tissues. Within the cells, testosterone undergoes enzymatic conversion to 5-alpha-dihydrotestosterone and forms a loosely bound complex with cystolic receptors. Androgen action arises from the initiation of transcription and cellular changes in the nucleus brought about by this steroid-receptor complex.
Normally, endogenous androgens stimulate RNA polymerase, resulting in an increased protein production.These proteins are responsible for normal male sexual development, including the growth and maturation of the prostate, seminal vesicle, penis, and scrotum. During puberty, androgens cause a sudden increase in growth and development of muscle, with redistribution of body fat. Changes also take place in the larynx and vocal cords, deepening the voice. Puberty is completed with beard development and growth of body hair. Fusion of the epiphyses and termination of growth is also governed by the androgens, as is the maintenance of spermatogenesis. When endogenous androgens are unavailable, use of exogenous androgens are necessary for normal male growth and development.
Pharmacokinetics:
Testosterone is administered intramuscularly (IM), to the skin as a topical gel, solution, ointment or transdermal systems for transdermal absorption, by implantation of long-acting pellets, or via buccal systems.Testosterone is administered intramuscularly (IM); via subcutaneous injection; to the skin as a topical gel, solution, ointment or transdermal systems for transdermal absorption; by implantation of long-acting pellets, or; via buccal systems.
In serum, testosterone is bound to protein. It has a high affinity for sex hormone binding globulin (SHBG) and a low affinity for albumin. The albumin-bound portion freely dissociates. The affinity for SHBG changes throughout life. It is high during prepuberty, declines during adolescence and adult life, then rises again in old age. The active metabolite DHT has a greater affinity for SHBG than testosterone. Elimination half-life is 10—100 minutes and is dependent on the amount of free testosterone in the plasma.
Testosterone is metabolized primarily in the liver to various 17-keto steroids. It is a substrate for hepatic cytochrome P450 (CYP) 3A4 isoenzyme.1 Estradiol and dihydrotestosterone (DHT) are the major active metabolites, and DHT undergoes further metabolism. Testosterone activity appears to depend on formation of DHT, which binds to cytosol receptor proteins. Further metabolism of DHT takes place in reproductive tissues. About 90% of an intramuscular testosterone dose is excreted in the urine as conjugates of glucuronic and sulfuric acids. About 6% is excreted in the feces, largely unconjugated. There is considerable variation in the half-life of testosterone as reported in the literature, ranging from 10 to 100 minutes.2
Affected cytochrome P450 isoenzymes and drug transporters: CYP3A4, P-gp.
Testosterone is a substrate for CYP3A4 and is also both transported by and an inhibitor of P-glycoprotein (P-gp) transport.
Potential benefits of Testosterone Cypionate
The purpose of Testosterone Cypionate injections is to help regulate male hormone levels to help address problems related to low T. For men with low T or for Testosterone Cypionate bodybuilding, the benefits of Testosterone Cypionate injections can include:- an increased sex drive
- improved symptoms of ED
- more energy
- improved mood
- an increased sperm count
- Maintain muscle strength and quality
- Maintain bone density and strength
- Maintain libido and erections
- Energizing and improving your fitness
How should I use Testosterone Cypionate ?
Testosterone Cypionate doses are very flexible in terms of the user’s goals in question. Testosterone Cypionate doses can be tailored to any possible goal – cutting, bulking, lean mass cycles all alike. Variation between Testosterone Cypionate doses depending on the user’s goal.For example, the bodybuilding ranges of doses are generally required for an individual that wishes to bulk up or add lean mass. For the purpose of cutting and fat loss, it is generally not a requirement to venture very high in dose ranges due to the fact that the primary concern when engaging in fat loss is the preservation of muscle mass during a caloric deficit in which muscle loss is a risk without the use of anabolic steroids. In such a case, lower doses are usually all that is necessary.Testosterone Cypionate dose for ED
Within the field of medicine, prescription guidelines for Testosterone Cypionate doses for the purpose of adult male androgen deficiency (hypogonadism and andropause) is determined to be 50 – 400mg administered once every 2 – 4 weeks. The specific dose will always depend on the individual in question,Testosterone Cypionate doses also include that of Testosterone Replacement Therpay (TRT) doses. This is necessary in cycles where an individual wishes to stack an additional anabolic steroid with Testosterone Cypionate and have that anabolic steroid provide the muscle growth effects while Testosterone Cypionate takes on the supportive role of merely maintaining normal physiological levels of Testosterone. A dose of 100mg weekly of Testosterone Cypionate is considered a sufficient TRT dose. Any higher and the user begins to run the risk of increased aromatization from supraphysiological Testosterone Cypionate doses.
Testosterone Cypionate dose for bodybuilding
Base Performance Testosterone Cypionate Doses:
For the purpose of performance enhancement, base Testosterone Cypionate bodybuilding doses will fall in the 400-500mg per week range. In fact, for many men this is all they’ll ever need even if they’ve been using anabolic steroids for years. Testosterone Cypionate doses of this range are very well-tolerated by most healthy adult men and will work well continually cycle after cycle. If you’ve never run a cycle before, this is where you’ll want to start as it will help you determine your overall response.Higher Testosterone Cypionate Doses:
Higher Testosterone Cypionate bodybuilding doses above the base performance level are not uncommon. You will find many men who supplement with 600-1,000mg per week. Most men will still find the 600mg range to be very tolerable, but as the dose increases beyond this point the probability of side effects begins to greatly increase. When Testosterone Cypionate doses surpass the 1,000mg per week mark this will dramatically increase the probability. For the average gym rat, his Testosterone Cypionate doses will never need to leave the 400-600mg per week range. For those who live a more hardcore lifestyle, such as a competitive bodybuilder or someone who simply lives that lifestyle, his doses will reach higher levels. Such doses can be run safely but it will take a concentrated effort and educated use; caution is advised.Bodybuilding Testosterone cypionate is a long acting, single ester testosterone product. It has a length of 8 carbons, and is stored mostly in the adipose tissue when injected intra-muscularly. It is slowly and steadily released in the body after it is injected. The blood levels of cypionate peak 24-48 hours after injection and then decline slowly. The blood levels reach a steady point 12 days after initial injection and stay there for over three weeks. Cypionate is normally injected once a week, which makes the very lowest dose higher than half the peak dose at any given time. Any testosterone, as the king of mass builders, are cost effective products and important for any steroid stack. Used alone, the user can expect to see some significant gains. The long acting nature of cypionate allows the user to inject less frequently while maintaining stable blood levels. A long acting testosterone ester will be very helpful for your bulking needs, and cypionate is a product which is more simple than some of the other steroids out there. Not to say it is without its share of complications, but it's a good choice, especially for those new to enhanced bodybuilding. Discontinuing the product is not an option in case side effects occur, because it will continue to aggravate these side effects over extended periods of time due to the long length of action of this steroid. Ancillary drugs such as nolvadex, proviron, clomid and HCG may help, both during cycle and post cycle to help restore natural testosterone production. Testosterone cypionate does aromatize slightly more than sustanon, but when using either drug, one should be familiar with anti-estrogens such as nolvadex or clomid and use one of them when symptoms of gyno occur.
Female Testosterone Cypionate Dosage
The use of Testosterone Cypionate among female anabolic steroid users is very uncommon due to the fact that this is a strong androgenic compound, and virilization symptoms are of a high occurrence rate and tend to manifest very rapidly. Testosterone Cypionate, therefore, is not recommended for female use and there exists very little data on dosing practices with this compound.What should I know before taking Testosterone Cypionate?
You are not allowed to use Testosterone Cypionate if:- You have an allergy to testosterone or any other part of testosterone cypionate injection.
- you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- you are male and have breast or prostate cancer.
- you have any of these health problems: Heart disease, kidney disease, or liver disease.
- you are a woman. This medicine is not recommended for female use.
What should I know while taking Testosterone Cypionate?
There are some medicine,which is easy to interact with,please don’t use these products while taking Testosterone Cypionate:- medicines for diabetes
- -medicines that treat or prevent blood clots like warfarin
- -oxyphenbutazone
- -propranolol
- -steroid medicines like prednisone or cortisone
What should I know after taking Testosterone Cypionate?
- Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light.
- Keep all medicine out of the reach of children.
- Throw away any unused medicine after the expiration date.
- Do not flush unused medications or pour down a sink or drain.
- Do not share this medicine with anyone.
- Selling or giving away this medicine is dangerous and against the law.
- Testosterone Cypionate Cycles and Uses
What should I do if I miss a dose?
Use a missed dose as soon as you think about it.If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
Do not use 2 doses or extra doses.
Testosterone Cypionate Cycles and Uses
As with almost any Testosterone variant or derivative, Testosterone Cypionate cycles tend to almost always be utilized for the purpose of bulking, mass gaining, and strength gaining periods of training. Though its ideal use is for this purpose, this is not to say that it cannot be used effectively (albeit at a lower dosage) for cutting cycles where fat loss is the primary goal. For the purpose of bulking and/or gaining mass and strength, Testosterone Cypionate is usually employed at a higher dosage (approximately 500mg/week). It is usually utilized at this dosage for a period of 12 – 14 weeks due to its longer ester, and therefore longer half-life. Testosterone Cypionate possesses a half-life of around 10 – 12 days. By comparison, its close counterpart Testosterone Enanthate is almost the same, with a half-life of around 7 – 10 days.No matter the cycle goal, whether it is cutting or bulking, Testosterone Cypionate is usually utilized with and stacked with other anabolic steroids that possess very similar characteristics for obvious reasons. It is a common companion to compounds such as Deca-Durabolin (Nandrolone Decanoate), which is usually run for the same 10 – 12 week length as Testosterone Cypionate, and a ‘kickstarting’ compound such as Dianabol (Methandrostenolone) is usually included from the start of the cycle until it is discontinued at around week 4 or 6.
What other drugs could interact with this medication?
There may be an interaction between testosterone cypionate and any of the following:- adrenocorticotropic hormone (ACTH)
- corticosteroids (e.g., hydrocortisone, prednisone, methylprednisolone)
- cyclosporine
- dehydroepiandrosterone
- diabetes medications (e.g., chlorpropamide, glipizide, glyburide, insulin, metformin, nateglinide, rosiglitazone)
- propranolol
- warfarin
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
The Side Effects of Testosterone Cypionate
As an extremely well-tolerated hormone for most men, the side effects of Testosterone Cypionate are in many ways easy to control. When it comes to such adverse reactions, keep in mind they largely fall into the realm of possible and are by no means guaranteed. Even so, total dosing, genetic predispositions and your overall state of health will play a role.As for the side effects themselves, Testosterone Cypionate like all testosterone compounds carries a high level of aromatase activity; aromatization referring to the conversion of testosterone into estrogen. As estrogen levels rise, this can lead to gynecomastia (male breast enlargement) and excess water retention. This excess water retention can even negatively affect blood pressure. In-order to combat such effects, especially gynecomastia, many turn to Selective Estrogen Receptor Modulators (SERMs) such as Tamoxifen Citrate (Nolvadex) and for more serious protection Aromatase Inhibitors (AIs) such as Anastrozole (Arimidex). Without question, AIs are the most effective; however, they can also prove to be problematic when it comes to cholesterol and caution is advised.
Beyond these effects, Testosterone Cypionate can promote dihydrotestosterone (DHT) related side effects such as acne, hair loss and prostate enlargement; however, it should go without saying DHT steroids will be the prime culprits. In-order to provide protection, a 5-alpha reductase inhibitor such as Finasteride can be useful as it is an androgen suppressor and the androgen DHT is causing the problem. It must be noted; hair loss is only possible in men predisposed to male pattern baldness.
How to make drug Testosterone Cypionate from Testosterone Cypionate powder?
Here is the simple recipes of making Testosterone Cypionate(for reference)Each mL of the 100 mg/mL solution contains:
Testosterone Cypionate...........................................................................100 mg
Benzyl benzoate .........................................................................................0.1 mL
Cottonseed oil ............................................................................................736 mg
Benzyl alcohol (as preservative).............................................................9.45 mg
Each mL of the 200 mg/mL solution contains:
Testosterone Cypionate............................................................................200 mg
Benzyl benzoate...........................................................................................0.2 mL
Cottonseed oil............................................................................................. 560 mg
Benzyl alcohol (as preservative)..............................................................9.45 mg
Where to buy high purity Testosterone Cypionate powder online?
Testosterone Cypionate powder is a moderately popular compound within the anabolic steroid world, and often competes with Testosterone Enanthate for popularity. There should be no problems locating this product on the market, as it is quite common and also easily manufactured.Testosterone Cypionate can be purchased from online sources,prices may vary.In the market,the purity of Testosterone Cypionate powder is totally different,usually range from 60%--99% puirty,also there are pharmaceutical grade one,but usually better quality matches high price,cause it can produce more products.Compared to those powder with low purity,it's deserve to buy high purity one.
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